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The Science of Refined Food Addiction Print E-mail
Feature Articles - Food Addiction
Written by Kay Sheppard, MA, LMHC, CEDS   
Monday, 28 September 2009 15:56

“Show me a man who’s eating dessert, and I’ll show you a man who’s not drinking enough.”    —W.C. Fields

It seems Fields was an early observer of the sugar-alcohol connection. Is it possible that one can be as addictive as the other? Do refined carbohydrates trigger the addictive process? The term food addiction implies there is a physiological, biochemical condition of the body that creates craving for refined carbohydrates. We have come to understand that this craving and its underlying biochemistry is comparable to the alcoholic’s craving for alcohol. Science has begun to show us why. 

Research has shown that food addiction is a biogenetic condition. Dedicated to understanding the biological/genetic basis of ­alcohol addiction, Dr. Ernest Noble and colleagues at UCLA have linked dopamine receptor D2 A1 to addiction. Previously linked to alcohol, cocaine and nicotine addiction, the A1 form of the reward/pleasure gene DRD2 has also been linked to carbohydrate craving and compulsive eating. Noble and his team found that a deficit of these dopamine receptors would cause subjects to be reward or pleasure deficient. To compensate for this deficiency, they discovered that alcohol activated the fewer D2 dopamine receptors stimulating the dopamine reward or pleasure system. According to Dr. Noble, “It is well established that food (particularly carbohydrates), like alcohol, when consumed, increases brain dopamine levels.” He and his team conducted and published a study in 1994, where they found the DRD2 A1 allele to be associated with obesity. “Thus,” he says, “individuals with the A1 allele, having a paucity of D2 dopamine receptors, have a deficiency in their dopamine brain reward system. To compensate for this state, they consume excessive amounts of food which eventuates in the development of obesity” (Noble, 2009; Noble et. al., 1994).

Using brain imaging techniques, neuroscientist Gene-Jack Wang, MD, observed that overeating behavior in morbidly obese individuals is similar to the loss of control and compulsive drug use seen in drug-addicted subjects. He and his team used PET scans to see if obese subjects had similar brain deficits. They measured brain dopamine reward/pleasure receptor levels in subjects with body mass index more than 40. They found these morbidly obese subjects had reductions in dopamine receptors, which were similar to those they observed in drug-addicted subjects (Wang, 2009).

We now see that the brain of the food addict is predisposed to respond differently to addictive foods due to dopamine receptor deficiencies and that addictive foods stimulate and increase the transmission of the neurotransmitters dopamine and serotonin. When the brain is flooded with these neurotransmitters, euphoria results leading to the compulsive pursuit of a mood change by engaging repeatedly in episodes of binge eating. Tolerance builds, increasing the frequency and amounts of the substance needed.   

How do addictive food substances compare to other addictive chemicals? Addictive substances are forms of plant life which have been refined or pro­cessed in order to be ingested by drinking, eating, inhaling or injecting. The refinement process facilitates quick absorption of substances into the blood stream which effectively alters brain chemistry and changes mood by flooding the brain with the neurotransmitters serotonin and dopamine. Food addicts seek this mood change by eating refined and processed carbohydrates. This results in short-term highs,  followed by a long period of depressed feelings. In order to avoid the low, the addict eats more. The food addict eats to feel better and always feels worse due to this flooding and depleting of neurotransmitters (Sheppard, K., 2000).

As with all addictions, treatment and recovery are based upon abstinence from all addictive trigger substances. The need to abstain from addictive substances is common to both alcoholics and food addicts. Treatment of food addiction begins by introducing the concept of abstinence from addictive food substances.

But could sugar really be as addictive as cocaine? The findings of Serge Ahmed, PhD, University of Bordeaux, France, a scientist who specializes in addiction research, clearly demonstrate that intense sweetness can surpass cocaine reward, even in drug-sensitized and -addicted individuals. His cocaine-addicted laboratory rats consistently chose sugar over cocaine (Lenoir, M., Serre, F., Cantin L. & Ahmed, S.H., 2007).

Studies using laboratory rats demonstrate that the characteristics of sugar addiction are similar to the binging, withdrawal and craving experienced in drug addiction. These findings further indicate that sugar is potentially as addictive because it is a substance that acts on brain circuits such as the dopamine and opioid pathways (Avena, N.M., Rada, P. & Hoebel, B.G., 2008).

Most of our food supply has been processed and refined to point that it has become more a drug and less a nutrient. Although alarming, it is no surprise to see our country moving toward more refined and processed foods. Whole aisles of food in the grocery store contain no whole foods. The poor quality of our food supply is causing an increase in obesity and other health-related issues. For food addicts, these highly refined foods act as mood-altering drugs with extensive negative health consequences. Refined food choices contribute to serious health issues—physical, mental and emotional—creating a health care crisis. Nancy Appleton, PhD, lists “140 reasons why sugar is ruining your health,” in her recently released book, Suicide by Sugar. Her well-researched list includes many health problems that could be eliminated by abstaining from refined and processed carbohydrates (Appleton, N., 2009). 

You don’t have to be a researcher to recognize the poor quality of our food. In his 2005 standup special, comedian Bill Maher said: “Last year we passed in our Congress this giant Medicare entitlement prescription drug bill. . .and it’s going to cost literally trillions and trillions of dollars. And while they were debating this, nobody ever stood up and said, ‘Excuse me, but why are we so sick?’ Could it be that we eat like Caligula? . . . Folks, it’s the food. I know that people hate to hear that, but when you look at those ads on the evening news at night, people . . . burping and bloating . . . Take a hint . . . You’re not going to die from ­secondhand smoke, or SARS or monkey pox. It’s the food. The call is coming from inside the house. The killer is not West Nile or Avian Flu or shark attacks. It’s the buffalo wings. It’s the aspartame and NutraSweet, and the red dye number two and the high fructose corn syrup and the MSG and the chlorine and whatever . . . is in the special sauce.”

Why is this phenomenon such a secret? For two reasons: denial and deception. Most people don’t want to know what they really need to know about nutrition, and are resistant to changing eating patterns. Because refined and processed foods are available in huge quantities and are marketed with such compelling advertising, the general population does not know, or does not want to know how destructive these foods are to our health and well-being. This is denial, delusion and lack of education in action. How many people watched Morgan Spurlock’s health decline in the documentary film, Super Size Me, and continued to eat fast food? Briefly following the release of that film, the fast food business went on a “health kick” but their good intentions were quickly dismissed when those so-called healthy salads were found to be high in saturated fat, calories and sodium. 

The other reason for the declining quality of our food supply and the resulting health issues is due to outright deception by food processors. Many years ago, I had a conversation with a sweetener distributor who told me that it had been recommended at a food processors convention that, “if you put more sugar in your product, people will buy more.” This “wisdom” has been taken to the ultimate degree. When we walk through grocery stores we see aisle after aisle of food that is virtually unfit for human consumption. One of our finer grocery stores here in Florida has only half an aisle of “health foods” and a three foot section of organic vegetables. That is no surprise because more than 1.6 billion dollars a year are spent marketing junk food to our kids (Federal Trade Commission, 2008).

Our nation’s increasing epidemic of obesity tells only part of the story about the effect of refined and processed foods on our population. Obesity is obvious. What is not obvious is the normal or underweight person who uses unhealthy measures to control weight: drugs, smoking, purging, restrictive diets and excessive exercise. Food abusers and food addicts can come in any size or shape; the health of our entire nation is being undermined by the quality of our food supply. Advocates for healthy eating, Dr. Kelly Brownell and Katherine Battle Horgen, in their book,  Food Fight: The Inside Story of the Food Industry, America’s Obesity Crisis & What We Can Do About It, outline bold public policy initiatives for reversing the obesity epidemic and  present steps individuals can take to safeguard their health in a culture that feeds its pets better than its children (Brownell, K. & Horgen, K.B., 2003). Unhealthy foods are cheaper, readily available, extensively marketed, and often subsidized by your tax dollar. 

The job is daunting. 
The findings of a report entitled Annual Medical Spending Attributable To Obesity: Payer- And Service-Specific Estimates, by Eric A. Finkelstein, Ph.D.; Justin G. Trogdon, Ph.D.; Joel W. Cohen, Ph.D.; and William Dietz, M.D., Ph.D., show that medical spending on conditions associated with obesity has doubled in the past decade, and is estimated to have reached an annual rate of $47 billion in 2008. From 1998 to 2006, annual medical costs due to obesity increased from 6.5 percent to 9.1 percent. In 2006, obese individuals spent 42 percent more (about $1,429) for medical care than did individuals of normal weight.

Traditionally, food addiction has been treated as an “eating disorder” using the Diagnostic and Statistical Manual for Eating Disorders for diagnostic and treatment purposes. This has not been found to be effective for food addicts.  Food addiction more accurately fits the criteria for substance dependence (Sheppard, K., 2000). According to the DSM-IV, substance dependence is a maladaptive pattern of substance use which leads to clinically significant impairment or distress. It is characterized by tolerance, withdrawal symptoms, substance use in larger amounts or for a longer duration than intended, attempts to cut back, excessive time spent pursuing, using or recovering from use, reduction or discontinuation of important activities because of use, and continued use despite adverse consequences (American Psychiatric Association, 1994). Overeating can be described as an addiction to refined foods that conforms to the DSM-IV criteria for substance use disorders (Ifland, et al., 2009).
In the early 1980s, clinicians stepped out of the Eating Disorders Box and commenced using the addictions model of treatment for food addicts.

The first steps of such treatment are to break the binge cycle, support through withdrawal and introduce the concept of abstinence from refined and processed foods. The next stage is to provide accurate information about the nature of food addiction—a disease that is primary, chronic, progressive and potentially fatal. The client is encouraged to identify how food addiction affected his or her life and as well as the lives of family members. Orientation to recovery support programs, relapse prevention techniques and development of an ongoing support system help to ensure continuing recovery (Sheppard, K., 1993). We have learned that every healthy choice—whether it is physical, mental or spiritual in nature—is a good recovery choice that heals the addicted brain. 

Kay Sheppard, MA, a licensed mental health ­counselor and certified eating disorder professional, pioneered development of the concept of food addiction. Her best-selling books Food Addiction: The Body Knows; From the First Bite: A Complete Guide to Recovery from Food Addiction and Food Addiction: Healing Day by Day, have become primary resources for food addicts, and addiction professionals. She conducts workshops worldwide, and has an online support recovery forum with a membership of over  5,000 men and women. Visit her website at www.kaysheppard.com, or write her at This e-mail address is being protected from spambots. You need JavaScript enabled to view it .

References
American Psychiatric Association (1994). Diagnostic and statistical manual of mental disorders (4th Ed.). Washington, DC.
Appleton N. (2009). Suicide by Sugar. Garden City Park, NJ.
Avena N.M., Rada P. & Hoebel B.G. (2008). Evidence for sugar addiction: Behavioral and neurochemical effects of ­intermittent, excessive sugar intake. Neuroscience and Biobehavioral Reviews, 32 (2008).
Brownell, K. & Horgen, K.B. (2003). Food Fight: The Inside Story of the Food Industry, America’s Obesity Crisis & What We Can Do About It. Columbus, OH, McGraw-Hill.
Federal Trade Commission Report (2008). Marketing Food to Children and Adolescents, A Review of Industry Expenditures, Activities, and Self-Regulation, Appendices, Washington, D.C.
http://foodaddictionsummit.org/presenters-noble.htm 
http://foodaddictionsummit.org/presenters-wang.htm 
Ifland, J.R., Preuss H.G., Marcus M.T., Rourke K.M., Taylor, W.C., Burau, K., Jacobs W.S., Kadish, W. & Manso G. (2009). Refined food addiction: A classic substance use disorder. Medical Hypotheses 72 (2009). 
Lenoir, M., Serre, F., Cantin, L. & Ahmed, S.H. (2007). Intense Sweetness Surpasses Cocaine Reward. PLoS ONE 2(8): e698. doi:10.1371/
journal.pone.0000698.
Noble, E.P., Noble, R.E., Ritchie, T., Syndulko, K., Bohlman, M.C., Noble L.A., Zhang, Y., Sparkes, R.S. & Grandy, D.K. (1994). D2 Dopamine Receptor Gene and Obesity. International Journal of Eating Disorders, Vol. 15, No.3. 203-217.
Sheppard, K. (1993). Food Addiction: The Body Knows. Deerfield Beach FL, Health Communications, Inc.
Sheppard, K. (2000). From the First Bite. Deerfield Beach FL, Health Communications, Inc.

This article is published in Counselor, The Magazine for Addiction Professionals, October 2009, v.10, n.5, pp.22-25.

Comments
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Rose  - 100% true   |65.89.98.xxx |2010-03-11 06:44:15
At 5'1" I weighed in at 265 lbs just three years ago (size 26). I'm now 125
lbs, size 4. The reason? I walked away from addictive foods - cheese, fat, and
sugar. I initially learned about the science of food addiction from Dr. Neal
Barnard, who has written several books on the subject. I learned about the
dopamine receptors, that cheese has trace amounts of a form of morphine, etc.,
although I didn't know until recently that this can actually be a genetic
predisposition, which would help explain why some people are more susceptible
than others. At any rate, it's not about blaming bad genes or the food industry
for our weight; it's about educating yourself about what's out there and what
effect it can have so that you can make an informed decision on how to handle
it. This is such excellent information that NEEDS to become mainstream
knowledge if we're going to stop the obesity epidemic.
Stephanie Zimmerman  - THIS IS THE TRUTH!   |208.39.156.xxx |2009-10-05 09:34:17
I fought the battle with food time and time again and I ALWAYS lost. I lost
until I became 370lbs. I went to doctors, psychologists, psychiatrists - you
name it. Every "diet" program out there from counting points to buying
"special" food did not do the trick either. They worked here and there,
but never for the long term. I remember telling the professionals that if I
never ate dessert or junk food again it would be better. But they balked and
told me the answer is in moderation and that I would just set myself up for a
binge. Hmmm, my body knew back then... Then I read Food Addiction: the Body
Knows by Kay - I began the food plan which is free of ALL addictive substances -
I joined her online yahoo group and a local support group and miracle of
miracles, the insanity stopped. The cravings stopped and I was freed of over
200 lbs in less than 2 years. Please people, SHARE this information. I was at
jac  - food addiction   |75.39.136.xxx |2009-10-05 03:45:47
we knew all along
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